Treatment of female infertility

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The treatment for female infertility depends on the cause. This will be discussed with you by your doctor after proper evaluation. Adequate medical history from the affected patients and examination, in addition to the investigations listed above will help in getting appropriate medical advice on treatment modalities.

1. Correction of hormonal imbalance

This will ensure that ovulation takes place, making egg available for fertilization. 

2. Ovulation induction 

Sometimes, in addition to correcting the hormonal imbalance, it may be necessary to induce ovulation. This is done to ensure the availability of eggs for sperm to fertilize, especially where there is doubt about ovulation in the affected woman, without any obvious cause or after correcting the supposed cause

Agents used for ovulation induction include:

  1. Chlomiphene citrate
  2. Letrozole
  3. Synthetic follicle stimulating hormone with human chorionic gonadotropin
  4. Gonadotropin releasing hormone agonist or antagonist

3. Surgery

This may be necessary:

  1. To open the cervix or endometrial cavity following adhesion or incomplete canalization; 
  2. For fibroid removal – this may be necessary in a situation where no other cause for infertility is found in a woman with fibroids large enough and in a location to cause infertility; 
  3. For removal of ovarian cyst – ovarian cyst may impair ovulation, and treatment of such cysts may allow the woman to ovulate. 
  4. Gonadotropin releasing hormone agonist or antagonist

4. Assisted reproductive technology

This may be with the woman’s eggs or donor eggs. The woman’s eggs may be used if she is less than 35 years of age and there are no undesirable family characteristics to avoid. Donor eggs will be preferred if the woman is older or there are undesirable heritable characteristics in the family which the woman may wish not to pass to her offspring.  

5. Adoption

This may be necessary in a situation where:

  1. Male or female infertility is not amenable to medical or surgical treatment,
  2. The couple does not have money for assisted reproductive technology, or
  3. Assisted reproductive technology has failed or is not feasible for whatever reason. Every country / state has laws guiding legal adoption. It is advisable to follow legal means in adoption to avoid untoward consequences later.

6. Surrogacy

This represents a situation where a woman carries pregnancy for another woman. It is done mainly through assisted reproductive technology. This may be an option if the woman: 

  1. Has no uterus or lost her uterus to disease condition related or unrelated to pregnancy or 
  2. Has disease conditions that will be worsened by pregnancy. 

For this procedure case, the woman’s eggs are fertilized by her husband’s sperm cells and made to germinate outside the uterus for three to five days. This is then transferred into the woman who has accepted to carry the baby for the woman.

For this method to be successful, the woman to carry the pregnancy is prepared through some forms of hormonal treatments before the growing baby is transferred into her.

This method may be fraught with legal issues after delivery of the baby, as the woman who carried the pregnancy may later claim the baby to be hers. Therefore, there should be legal documentations before this method is embarked upon.

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